About

This blog is created mainly to share software developed by me.

I am a research scientist at Janssen Pharmaceutical Companies of Johnson&Johnson. My research involves protein structure and function studies using experimental and theoretical methods. My expertises lie in protein biochemistry, mass spectrometry, hydrogen-deuterium exchange, computational biology, and electron paramagnetic resonance spectroscopy.

Education

Postdoc in Biophysics/Biochemistry, Albert Einstein College of Medicine, NY.
Ph.D. in Molecular Biophysics, Florida State University, Tallahassee, FL.
B.S. in Physics, Bilkent University, Ankara, Turkey.
Internship at University of Twente, Enschede, the Netherlands.

Publications

  • Sen KI, Wu H, Backer JM, Gerfen GJ (2010) “The Structure of p85ni in Class IA Phosphoinositide 3-Kinase Exhibits Interdomain Disorder” Biochemistry 49(10): 2159-2166. PMID:20131869
  • Wu H, Sen KI, Gerfen GJ, Backer JM (2009) “Regulation of Class IA PI 3-kinases: C2 domain-iSH2 domain contacts inhibit p85/p110 and are disrupted in oncogenic p85 mutants.” Proc Natl Acad Sci USA. 106(48): 20258-63. PMID:19915146
  • Sen KI, Fajer PG (2009) “A statistical approach to analyze double electron-electron resonance data using the DEFit software.” EPR Newsletter 19(1-2): 26-27. PDF
  • Sen KI, Logan TM, and Fajer PG (2007) “Protein dynamics and monomer-monomer interactions in AntR activation by electron paramagnetic resonance and double electron-electron resonance” Biochemistry 46: 11639-11649. PMID:17880108
  • Fajer PG, Gyimesi M, Malnasi-Csizmadia A, Bagshaw CR, Sen KI, and Song LK (2007) “Myosin cleft closure by double electron-electron resonance and dipolar EPR” J Phys-Condens Mat 19:285209-285218. doi:10.1088/0953-8984/19/28/285208
  • Sen KI, Sienkiewicz A, Love JF, vanderSpek JC, Fajer PG, and Logan TM (2006) “Mn(II) Binding by the Anthracis Repressor from Bacillus anthracis” Biochemistry. 45: 4295-4303. PMID:16566604

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